Sydney Klein

Sydney Klein is a seasoned technology and cybersecurity executive with more than 25 years of experience across the life sciences and financial services sectors. She is widely recognized as a thought leader for her role in building secure, resilient and innovative technology organizations at scale.

Currently, as Global Chief Information Security Officer (CISO) and Head of Enterprise IT at Bristol Myers Squibb (BMS), Sydney leads the company’s global efforts to deliver a seamless digital experience that balances innovation and security while protecting the company’s most valued information. Her responsibilities span a wide range of technology areas, including cybersecurity, cloud, infrastructure, enterprise data platforms, artificial intelligence (AI), engineering, digital workforce experience, corporate function technology, employee collaboration and productivity, and more.

A recognized leader in the advancement of AI, Sydney has championed its responsible integration across the organization, driving innovation while rigorously safeguarding data security and privacy. Under her leadership, BMS has pioneered strategic initiatives that leverage AI to enhance operational efficiency, deliver transformative business outcomes, and unlock significant productivity enhancements that empower its workforce to concentrate on the work humans do best.

Beyond her technical leadership, Sydney spearheaded the development and launch of BMS’s AIQ education program, an enterprise-wide initiative designed to empower employees with critical AI knowledge and skills. Through curated learning modules, hands-on workshops, and ongoing mentorship, AIQ has helped foster a culture of digital literacy and responsible AI adoption throughout the company, positioning BMS and its workforce at the forefront of pharma’s AI transformation.

Prior to joining BMS, Sydney served as Vice President of Cyber at Capital One Financial, where she developed, launched, and scaled a range of high-impact enterprise cybersecurity and data programs over nearly two decades. Her work helped mature critical capabilities across areas such as data management, cybersecurity operations, and cyber incident reporting, several of which became industry benchmarks.

In addition to her work at BMS, Sydney was appointed to the Board of Directors at BioCT, a life sciences trade organization for the state of Connecticut, in 2026.

Sydney has been an active member of Global Inclusion Councils, where she has guided the company’s inclusion strategy to enhance business results. She is a sought-after speaker and thought leader, having spoken at numerous events, including the Wall Street Journal Pro Cybersecurity Forum, the Reuters Momentum AI Conference, and the Google Health Sector Security and Resilience Symposium. Sydney has been honored with several awards, including the New Power Women of D.C. in 2017, Top 100 Women in Business in 2022, Top 10 CISOs in 2022 and 2023, Top 100 Women in Cyber 2024, and as a New York CISO ORBIE finalist in 2025. She also participated in a Congressional Black Caucus Foundation “Braintrust” summit that focused on using AI to address care disparities in 2025. In 2026, Sydney was selected as a Healthcare Businesswomen Association (HBA) Luminary.